1. Restoration of the gut microbiota

Dysbiosis of the intestinal microbiota is commonly caused by pathogenic infections and also due to a loss of commensal microbiota which can facilitate the growth of opportunistic pathogens, for example after antibiotic consumption.

The colonization of the gut by the probiotic microorganisms has a protective effect on the intestinal microbiota and is a defense mechanism against pathogens that may cause diarrhea.

Binding to intestinal surfaces is considered a key probiotic trait for bacterial strains to be able to achieve a beneficial effect. Thanks to this capacity, probiotics can prevent intestinal colonization by opportunistic pathogens by competing for binding sites. In addition, probiotics can compete for the available nutrients in the gut, reducing the growth of these enteropathogens.

3. Prevention of diarrhea

Helps preventing from acute GI symptomatology such as infectious diarrhea episodes and antibiotic-associated diarrhea.

Probiotics helps preventing and treating gastrointestinal infections.

The use of antibiotics is the most common cause for major change in normal intestinal microbiota. Antibiotic therapies destroy members of the microbial community creating an environment susceptible to pathogenic and opportunistic agents.

Diarrhea can also be caused by virus infections such as Rotavirus and bacterial infections such as Listeria and Salmonella.

2. Strengthening and stimulation of the good function of the intestinal flora

The formula used in Pur Natur bio activ yoghurt helps reinforcing the intestinal flora. The intestinal epithelium and mucosa are physical barriers that regulate the exchange of nutrients and water between the external environment of the intestinal lumen and the body. This mucosal barriers can be affected by an inflammation process. This would result in a passive loss of both water and solutes from the body into the intestinal lumen leading to diarrhea.

Epithelial/mucosal barrier can be also compromised by viral infections. Several viruses, especially rotavirus, can infect the intestinal cells, resulting a loss of intestinal villi, which in turn causes a loss of surface area available for the exchange and absorption of water, electrolytes and nutrients. This situation can cause vomiting and diarrhea involving significant loss of water that ultimately can lead to dehydration. Several clinical studies show the effectiveness of some Lactobacillus rhamnosus GG in the prevention and treatment of diarrhea caused by rotavirus in children. Its protective effect is attributed to its ability to reduce both replication and adhesion of the virus to the epithelial cells in the mucosa. Additionally, some studies show that the protective effect of Lactobacillus rhamnosus GG against viral infections can be even higher if administered preventively before the infection occurs.